The Reliability and Validity of Visual Assessment for Pressure-time Curve
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- the types of pressure time curve by visual inspection.
研究概览
简要总结
Airway pressure-time (P-t) curve and stress index (SI) assessment have been proposed to guide the mechanical ventilation settings and minimize ventilator-induced lung injury.
详细描述
The stress index (SI), which has been proposed to guide the mechanical ventilation settings and minimize ventilator-induced lung injury. It reflects the change of respiratory compliance during inspiration. Value of SI equals to 1 that indicates a constant compliance, whereas values lower and higher than 1 indicate increase and decrease of compliance over inspiratory time, suggesting tidal recruitment and tidal hyperinflation, respectively. Based on the different values of SI showing different shapes, SI of straight curve equals to 1, SI of concave curve lower than 1 and convex curve higher than 1, the investigators speculated that the SI value could be reliably and accurately estimated by visual inspection of the P-t curve.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •aged 18 years or older; intubated and mechanical ventilated by volume-control ventilation with constant flow;
排除标准
- •evidence of active air leak from the lung, including bronchopleural fistula, pneumothorax, pneumomediastinum, or existing chest tube; evidence of the stiff chest wall, such as existing the pleural effusion, intra abdominal hypertension, chest injuries and abdominal injuries.
结局指标
主要结局
the types of pressure time curve by visual inspection.
时间窗: up to 10min, from the ventilator screen being frozen to the two observers completing judgement.
the pressure time curves have the three types:the straight,concave,convex,the observers will judge the types of pressure time curve by visual inspection, and record the results of judgement
次要结局
未报告次要终点
研究者
Jian-Xin Zhou
Professor
Capital Medical University