Intrathecal analgesia in patients undergoing major hepatobiliary surgery

Not Applicable

Completed

• Conditions: iver resection; Analgesia following liver resection; Liver resection; Surgery - Surgical techniques; Anaesthesiology - Pain management; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon; Cancer - Liver

• Registration Number: ACTRN12620000001998
• Lead Sponsor: Austin Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2018-12-08
• Study Start: 2020-01-08
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 335

Inclusion Criteria

All adult patients who underwent surgery at Austin hospital in Melbourne, Eligible patients were identified by International Statistical Classification of Diseases (ICD) codes that included the following surgical categories: i.) excision of lesion of liver, ii.) segmental resection of liver, iii.) lobectomy of liver, iv.) trisegmental resection of liver, and v.) segmental resection of liver for trauma.

Exclusion Criteria

We will excluded patients with a history of chronic opioid use (defined as near-daily use of >60 mg oral morphine equivalent) for 8 weeks or longer and patients receiving epidural analgesia.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome was cumulative oral morphine equivalent daily dose in milligrams (oMEDD) on post operative Day 1. [Oral morphine equivalent daily dose in milligrams amounts will be collected from the patient's hospital electronic medical record. Oral morphine equivalent will be calculated using the Opioid Dose Equivalence document endorsed by the Faculty of Pain Medicine, Australian and New Zealand College of Anaesthetists]