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COMPARISON BETWEEN KETOPROFEN AND KETOPROFEN WITH DOXYCYCLINE GEL AS LOCAL DRUG DELIVERY IN SMOKERS AND NON SMOKERS CHRONIC PERIODONTITIS PATIENTS.

Phase 2
Completed
Conditions
Health Condition 1: K053- Chronic periodontitisHealth Condition 2: F172- Nicotine dependence
Registration Number
CTRI/2020/03/024280
Lead Sponsor
MANUBHAI PATEL DENTAL COLLEGE AND ORALRESEARCH INSTITUTE
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
21
Inclusion Criteria

(1) at least 20 natural teeth present

(2) probing depth of at least 4mm and clinical attachment loss of at least 2mm in all quadrants of the mouth.

(3) smokers group having subjects smoking at least 10 cigarettes/bidis per day

(4) non smokers group having subjects who have never smoked cigarettes or any other form of tobacco.

(5) willingness to comply with the study protocol.

Exclusion Criteria

(1) existing systemic disease that may affect the severity or progression of periodontal disease.

(2) medication consumption that may influence the periodontium (e.g. non steroidal anti-inflammatory drugs or antibiotics) within 6 months preceding the beginning of intervention.

(3)subjects undergoing orthodontic treatment or extensive restorations

(4) patients with aggressive periodontitis or multiple caries

(5) patients during pregnancy or lactation

(6) patients allergic to doxycycline or ketoprofen

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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