Screening Cardiovascular Patients for Aortic Aneurysms

Completed

• Conditions: Abdominal Aortic Aneurysm

• Registration Number: NCT01643317
• Lead Sponsor: Catharina Ziekenhuis Eindhoven

Brief Summary

Screening studies for Abdominal Aortic Aneurysms (AAA) in 65 to 79 years aged men, have shown a significant reduction in AAA related mortality. In addition, the cost-effectiveness of screening for AAA in men in the Netherlands has been demonstrated by using a Markov model. Screening might be even more (cost-) effective if targeted on high risk groups, such as patients with a particular cardiovascular disease with a known increased risk of having an AAA.

Project SCAN (Screening CardioVascular patients for Aortic aNeurysms) is a project focused on targeted AAA screening to proactively diagnose patients at high risk of having an aneurysm that eventually may rupture. This pilot project aims to study the value of a screening protocol in daily practice to detect AAA's in high risk patients.

Detailed Description

1. Offering PAD and CAD patients a non-invasive abdominal ultrasound after a careful process of shared-decision making

2. Recording data on aneurysm detection on all PAD and CAD patients screened:

1. General information (age, gender)

2. Medical history on CardioVascular risk factors (such as smoking history, hypertension, and other cardiovascular medical conditions - only information that is already recorded in the patient's medical history chart)

3. AAA - Yes/ No (Yes if ≥3 cm AAA)

4. If ≥3 cm aneurysm, record exact size and outcome in time (surveillance, treatment, no treatment)

5. If treated, record treatment type (EVAR or Open) and outcome

Study Timeline

• Study Start: 2012-07
• Study First Submitted: 2012-07-16
• Study First Submitted QC: 2012-07-17
• Study First Posted: 2012-07-18
• Primary Completion: 2013-07
• Study Completion: 2013-07
• Status Verified: 2019-07
• Last Update Submitted: 2019-07-23
• Last Update Posted: 2019-07-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

• male and female patients
• peripheral arterial disease (ankle brachial index < 0,90 and/or reduction of > 0.15 after exercise test) or a carotid stenosis (stenosis ≥ 50%)
• age > 55 year

Exclusion Criteria

• Patients unfit for endovascular or open surgery (as judged by vascular surgeon)
• Failure to master the dutch language

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
AAA prevalence	1 year

Trial Locations

Locations (1)

Catharina Hospital; 🇳🇱 Eindhoven, Netherlands