Effect of non-invasive ventilation during exercise on dynamic hyperinflation in chronic obstructive pulmonary disease

Completed

• Conditions: chronic obstructive pulmonary disease; Respiratory - Chronic obstructive pulmonary disease; Physical Medicine / Rehabilitation - Physiotherapy

• Registration Number: ACTRN12613000804785
• Lead Sponsor: niversity of Sydney

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-07-22
• Study Completion: 2019-05-20
• Last Update Posted: 3 February 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

Diagnosis of severe to very severe COPD (FEV1/FVC < 70%, FEV1 < 50% predicted)

Stable over the past month (i.e. no admissions to hospital, change in medications or increase in respiratory symptoms)

Exclusion Criteria

Concomitant cardiovascular, orthopaedic or neurological conditions that are likely to impair exercise performance

Other significant pulmonary disease (e.g. asthma)

Major psychiatric illness

Inability to give informed consent

BMI > 32 kg/m2

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Change in inspiratory capacity measured by spirometry<br><br> The patients breathing will be monitored the entire test via a flow transducer placed at the outlet of the mask[End of exercise]<br> ;Endurance Time as measured by time since work load was added to the cycle ergometer[End of Exercise]

Secondary Outcome Measures

Name	Time	Method
<br> Minute Ventilation as measured using spirometery<br><br> The patients breathing will be monitored the entire test via a flow transducer placed at the outlet of the mask[End of exercise]<br>