Efficacy Of Losartan In Treatment Of Hyperuricemia After Renal Transplantatio
Phase 2
- Conditions
- Compliations Of Kidney Trasplantation.Kidney Transplant Status
- Registration Number
- IRCT201111108032N1
- Lead Sponsor
- Research Assistance Of Tabriz University Of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Post renal transplant patients; Normal and stable renal function; Completion of testimonial
Exclusion criteria: Transplanted renal artery stenosis; Acute rejection episode during last month; cardiovascular or cerebrovascular complications during last month or any abnormality in cardiac, lung or liver function; taking ACEIs , ARBs or any uric acid lowering agent and during study; more than 50% rise in serum creatinine; systolic blood pressure less than 90mmHg or diastolic blood pressure less than 60mmHg; Hb less than 100gr/
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum uric acid level. Timepoint: before taking Losartan,1st,2d,3rd &6th month. Method of measurement: laboratory.
- Secondary Outcome Measures
Name Time Method Serum potassium concentration. Timepoint: before taking Losartan,1st,2d,3rd &6th month. Method of measurement: laboratory.;Serum creatinine level. Timepoint: before taking Losartan,1st,2d,3rd &6th month. Method of measurement: laboratory.;Urea nitrogen level. Timepoint: before taking Losartan,1st,2d,3rd &6th month. Method of measurement: laboratory.;Hemoglobin. Timepoint: before taking Losartan,1st,2d,3rd &6th month. Method of measurement: laboratory.;Whole-blood CSA through level. Timepoint: before taking Losartan,1st,2d,3rd &6th month. Method of measurement: laboratory.;Serum albumin. Timepoint: before taking Losartan,1st,2d,3rd &6th month. Method of measurement: laboratory.