Early Multimodal Neuromonitoring For Spontaneous Intracerebral Hemorrhage (ICH)

Completed

• Conditions: Intracerebral Hemorrhage; Critically Ill; Cerebral Perfusion Pressure; Intracranial Pressure; Prognostic

• Registration Number: NCT05501613
• Lead Sponsor: Universidade do Porto

Brief Summary

The investigators intend to assess the predictive value of early (first 48 hours) multimodal neuromonitoring parameters concerning late survival in critically ill intracerebral hemorrhage (ICH) patients.

Detailed Description

Retrospective observational study based on analyzing the first 48 hours of the multimodal neuromonitoring signal, from spontaneous ICH patients, whose treatment includes invasive intraparenchymal neuromonitoring, treated from January 2015 to September 2021 in a tertiary hospital.

Study Timeline

• Study Start: 2015-01
• Study First Submitted: 2022-08-11
• Study First Submitted QC: 2022-08-11
• Study First Posted: 2022-08-15
• Primary Completion: 2022-10-01
• Status Verified: 2023-02
• Study Completion: 2023-02-01
• Last Update Submitted: 2023-02-02
• Last Update Posted: 2023-02-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 65

Inclusion Criteria

• Spontaneous Intracerebral Hemorrhage
• ICU admission
• Need of Sedation and Ventilatory Support
• Need of Intracerebral Neuromonitoring

Exclusion Criteria

• Etiology for Intracerebral hemorrhage such as tumor, vascular malformation, ischemic transformation.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Survival	1 and 6 months	1 and 6 months survival
Functional Outcome	6 month	6 month functional outcome with Modified Rankin Scale - 0 (No symptoms); 1 (No significant disability); 2 (Slight disability); 3 (Moderate disability); 4 (Moderately Severe Disability); 5 (Severe Disability); 6 (Dead).

Trial Locations

Locations (1)

Centro Hospitalar Universitário de São João; 🇵🇹 Porto, Portugal