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Effect of gum-based bolus viscosities on the safety of swallowing in patients with chronic post-stroke oropharyngeal dysphagia

Conditions
Dysphagia
Registration Number
NL-OMON25638
Lead Sponsor
utricia Research BV
Brief Summary

n/a

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
120
Inclusion Criteria

1.Diagnosis of stroke, and minimum 28 days since stroke

2.Clinical signs or symptoms of swallowing dysfunction, based on Eating Assessment Tool (EAT-10) questionnaire, or bedside clinical test or water swallow test, or referral by medical doctor for Video FluoroScopy (VFS)-test, or current use of thickened products

Exclusion Criteria

1.Patients with respiratory insufficiency in need of additional oxygen

2.Dysphagia not related to stroke

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Percentage of subjects that swallow viscosity levels 1, 2 and 3 safely (PAS score 1,2) compared to thin iodine liquid control
Secondary Outcome Measures
NameTimeMethod
•Safety of swallowing per individual viscosity as measured by:<br /><br>•Percentage of subjects that swallow safely (PAS score 1,2)<br /><br>•Percentage of subjects with penetration (PAS score 3,4,5)<br /><br>•Percentage of subjects with aspiration (PAS score 6,7,8)<br /><br>•Mean PAS score<br /><br>•Efficacy of swallowing per individual viscosity as expressed by:<br /><br>•Presence and severity of oral residue (score 0,1,2) Presence and severity of pharyngeal residue (score 0,1,2)
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