Effect of Xylitol chewing gums on oral bacteria
Phase 4
Completed
- Registration Number
- CTRI/2018/03/012632
- Lead Sponsor
- The Oxford Dental College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Subjects who did not have any active carious lesions.
Subjects who were not on any systemic antibiotic medication, 3 months prior to the commencing of the study.
Subjects available for the entire duration of the study, willing to participate were included in the study.
Exclusion Criteria
Subjects who had recent exposure to topical or systemic fluoride treatment.
Subjects who were phenylketonurics.
Subjects who had a history gastro-intestinal problems.
Subjects who were habitual consumer of chewing gums.
Subjects who were undergoing any orthodontic treatment at the time of the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the action of 100% xylitol chewing gums at the dose and frequency used in our study in reduction of mutans streptococci and this strategy can be used as a targeted caries-preventive measureTimepoint: 30, 60 , 90 days
- Secondary Outcome Measures
Name Time Method Follow-up for measuring stretptococcus mutans count, salivary pH levels and buffering capacityTimepoint: 60 days and 90 days