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Clinical Trials/NCT04480528
NCT04480528
Completed
Not Applicable

The Effect of Various Strength Training Protocols in Female Runners With Patellofemoral Pain

Lauren Erickson1 site in 1 country20 target enrollmentJune 8, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Patellofemoral Syndrome
Sponsor
Lauren Erickson
Enrollment
20
Locations
1
Primary Endpoint
Change in Isometric Quadriceps Strength
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Patellofemoral pain (PFP) is a common running-related injury that is often referred to as runner's knee. The condition typically presents with pain in the front of the knee that is located around or behind the knee cap. This injury occurs twice as frequently in females and is often associated with weakness of the muscles of the thigh and hip, as well as altered running form. Heavy-weight strength training is needed in order to improve muscle weakness; however, this puts a significant amount of load on the knee joint and it is difficult for individuals with PFP to train at this level without experiencing increased pain and joint discomfort. Blood flow restriction training (BFRT) is a promising alternative method to safely improve muscle weakness while reducing knee joint loading. With BFRT, a pressurized band is applied to the thigh in order to partially restrict blood flow as a patient exercises in order to decrease the amount of oxygen delivered to the muscle. Lack of oxygen to the muscle combined with strength training creates an environment within the muscle that results in the ability of low-weight strength training to provide the same results as heavy-weight strength training.

This study will evaluate how low-weight strength training with and without BFRT affects thigh and hip strength, and consequently pain, function, running ability, and running form in female runners with PFP. The hypothesis is that 10 weeks of low-weight strength training with BFRT will lead to greater thigh and hip strength, reduced pain, improved knee function, improved running ability, and improved running form compared to low-weight strength training without BFRT. The expected results will have a significant impact within the running community by providing a safe and effective treatment that increases strength and improves running form while reducing pain and joint loading. This will also have an impact on the larger field of sports medicine by providing an alternative method to improve strength, as well as improve function when heavy-weight strength training is not well tolerated or unsafe due to injury.

Registry
clinicaltrials.gov
Start Date
June 8, 2020
End Date
November 13, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Lauren Erickson
Responsible Party
Sponsor Investigator
Principal Investigator

Lauren Erickson

Graduate Research Assistant

University of Kentucky

Eligibility Criteria

Inclusion Criteria

  • Pain around (peripatellar) or behind (retropatellar) the patella, which is aggravated by running and at least one other activity that loads the patellofemoral joint during weight bearing on a flexed knee such as kneeling, squatting, stair ambulation, and jumping/hopping
  • Insidious onset of symptoms unrelated to trauma
  • Pain present for at least 2 months
  • Pain rating of at least 3/10 on the visual analog scale during running
  • Report running at least 10 miles per week currently or just prior to onset of injury
  • Score a maximum of 85% on either the Knee Outcome Survey Activities of Daily Living Scale or Sports Activity Scale (KOS-ADL or KOS-SAS)

Exclusion Criteria

  • Knee pain resulting from acute trauma
  • Concurrent ligamentous instability, meniscus pathology, patellar or iliotibial band tendinopathy
  • History of patellar dislocations or instability, or previous reconstructive surgery to the knee
  • Other lower extremity or lower back injury within the past 6 months

Outcomes

Primary Outcomes

Change in Isometric Quadriceps Strength

Time Frame: 10 weeks

The subject will be seated in a Biodex 4 dynamometer with their knee locked at 90 degrees of flexion. The subject will be asked to kick into the dynamometer pad as hard as they can and the peak force will be measured and normalized to body weight. Increased force indicates greater quadriceps strength.

Change in Isometric Hip Extension Strength

Time Frame: 10 weeks

The subject will be lying on their stomach with their knee flexed to 90 degrees and a stabilizing strap placed around the thigh. The subject will be asked to press up as hard as they can against a handheld dynamometer which records the force applied against it. The peak force will be measured and normalized to body weight. Increased force indicates greater hip extension strength.

Change in Isokinetic Quadriceps Strength

Time Frame: 10 weeks

The subject will be seated in a Biodex 4 dynamometer and be asked to kick back-and-forth into the dynamometer pad as hard and as fast as they can. The peak force will be measured and normalized to body weight. Increased force indicates greater quadriceps strength.

Change in Isometric Hip Abduction Strength

Time Frame: 10 weeks

The subject will be lying in the side-lying position with a stabilizing strap placed around the thigh. The subject will be asked to press out as hard as they can against a handheld dynamometer which records the force applied against it. The peak force will be measured and normalized to body weight. Increased force indicates greater hip abduction strength.

Change in Isometric Hip External Rotation Strength

Time Frame: 10 weeks

The subject will be seated with their knee flexed to 90 degrees and a stabilizing strap placed around the lower leg. The subject will be asked to press inward as hard as they can against a handheld dynamometer which records the force applied against it. The peak force will be measured and normalized to body weight. Increased force indicates greater hip external rotation strength.

Secondary Outcomes

  • Change in Patellofemoral Pain: Knee Injury and Osteoarthritis Outcome Score(10 weeks)
  • Change in Hip Adduction Angle(10 weeks)
  • Change in Hip Internal Rotation Angle(10 weeks)
  • Change in Peak Knee Extensor Moment(10 weeks)
  • Change in Running Ability(10 weeks)
  • Change in Pain: Brief Pain Inventory (BPI)(10 weeks)
  • Change in Knee Function(10 weeks)

Study Sites (1)

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