Analgesic Effect of Peripheral Cutaneous Nerve Block of Knee Joint After Total Knee Arthroplasty
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Change of the pain score before and after surgery
研究概览
简要总结
Local anesthesia was performed on patients with total knee arthroplasty (TKA) through two different injection sites of local anesthetics and two local anesthetic drug . The pain score of patients after TKA was collected, then the analgesic effect of patients after TKA through two different injection sites and two different local anesthetic drug were analyzed and evaluated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients between the ages of 40-75, who meet the indications for total knee arthroplasty(TKA) surgery, plan to undergo unilateral TKA surgery, can tolerate surgical trauma, and have no surgical contraindications;
- •Patients who have good medical obedience and can cooperate to complete the evaluation of various indicators after the operation and continue to receive follow-up;
- •There is no contraindications to combined spinal-epidural anesthesia;
- •Agree to accept this trial and sign an informed consent form.
排除标准
- •Allergic to test drugs;
- •Abnormal liver, kidney or heart function;
- •People who have chronic pain symptoms in other parts of the body other than the knee joint;
- •Patients with a history of multiple operations on the knee joint, or patients with abnormal anatomical structures;
- •Patients who cannot perform early functional exercise after unconventional knee replacement or other systemic diseases;
- •Cannot communicate with researchers normally.
结局指标
主要结局
Change of the pain score before and after surgery
时间窗: pre-operation, 6hours after surgery, 24hours after surgery, 48 hours after surgery.
A Visual Analogue Scale (VAS) is used to measure the amount of pain that a patient feels ranges across a continuum from none to an extreme amount of pain. Using a ruler, the score is determined by measuring the distance (mm) on the 10cm line between the "no pain" anchor and the patient's mark, providing a range of scores from 0-100. A higher score indicates greater pain intensity.
次要结局
未报告次要终点
研究者
Diwuweilong
Principal Investigator
Xijing Hospital