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Clinical Trials/NCT02701296
NCT02701296
Completed
Not Applicable

Assessment of Knee Pain in Patients Receiving Continuous Femoral Nerve Block Combined With Either Ultrasound Guided Posterior Capsular Injection or Selective Tibial Nerve Block Following Total Knee Arthroplasty

Trinity Health Of New England1 site in 1 country80 target enrollmentNovember 7, 2011

Overview

Phase
Not Applicable
Intervention
Ropivacaine with Epinephrine
Conditions
Posterior Knee Infiltration
Sponsor
Trinity Health Of New England
Enrollment
80
Locations
1
Primary Endpoint
Pain Intensity
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

To assess pain control after total knee replacement surgery using two different nerve block techniques. The 2 methods are:

  1. Continuous femoral nerve block with ultrasound guided posterior capsular injection
  2. Continuous femoral nerve block with ultrasound selective tibial nerve block.

Detailed Description

Patients undergoing total knee replacement surgery experience severe post-operative pain. Continuous femoral nerve block combined with selective tibial nerve block provides optimal pain control in the anterior and posterior aspect of the knee respectively. However, in patients with pre-existing neuropathy of the sciatic nerve, the blockade of tibial nerve is contraindicated because of increased risk of nerve damage that may lead to exacerbation of neurologic symptoms. In such patients where selective tibial nerve block cannot be offered, ultrasound guided posterior knee capsular injection may be an alternative technique for controlling posterior knee pain after surgery. Posterior capsular injection by surgeons intraoperatively, when combined with femoral nerve block has been shown to provide pain control after total knee replacement. With posterior capsular injection, the main trunk of the tibial nerve is spared and only the terminal nerve endings innervating the posterior knee joint is blocked providing effective pain control. In this study, the efficacy of ultrasound guided posterior capsular injections performed pre-operatively will be compared to tibial nerve block in controlling knee pain after surgery. The results of this study may help establish the efficacy of ultrasound guided posterior capsular injection as an alternative to tibial nerve block in patients undergoing total knee arthroplasty.

Registry
clinicaltrials.gov
Start Date
November 7, 2011
End Date
August 31, 2014
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Trinity Health Of New England
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients having primary, unilateral total knee arthroplasty
  • Age 18-80

Exclusion Criteria

  • History of neurologic disease, neuropathy, diabetes, or major systemic illness
  • Allergy to local anesthetic solution or NSAIDs
  • Pregnancy
  • Chronic use of narcotics
  • Inability to give consent/cooperate with study

Arms & Interventions

Posterior capsular injection

Ultrasound guided posterior capsular injection of ropivacaine with epinephrine

Intervention: Ropivacaine with Epinephrine

Tibial nerve block

Ultrasound selective tibial nerve block of ropivacaine

Intervention: Ropivacaine

Outcomes

Primary Outcomes

Pain Intensity

Time Frame: 48 hours post surgery

Mean Numeric Pain Rating Scale (NPRS) self-reported pain Intensity on a 11-point score (0=no pain to 10= worst possible) in Post Anesthesia Care Unit (PACU) and every 6 hours for 48 hours post surgery

Secondary Outcomes

  • Opioid Consumption(24 hours post surgery)
  • Plantar Flexion in the Tibial Nerve Distribution(Upon emergence from anesthesia in the PACU)
  • Cold Sensation in the Tibial Nerve Distribution(Upon emergence from anesthesia in the PACU)
  • Dorsiflexion in the Peroneal Nerve Distribution(Upon emergence from anesthesia in the PACU)
  • Sensation in the Peroneal Nerve Distribution(Upon emergence from anesthesia in the PACU)

Study Sites (1)

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