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临床试验/NCT01225484
NCT01225484Unknown4 期

Perioperative Analgetic Therapy After Knee Arthroplasty

Landeskrankenhaus Feldbach2 个研究点 分布在 1 个国家目标入组 123 人开始时间: 2010年10月最近更新:
适应症

试验速览

阶段
4 期
入组人数
123
试验地点
2
主要终点
Static and dynamic pain scores (VAS)

研究概览

简要总结

The purpose of this study is to compare two accepted methods of pain control in knee arthroplasty surgery.The first method combines the periarticular injection of ropivacaine with continuous blockade of the femoral nerve.The second method uses periarticular infiltration of ropivacaine in combination with an bolus of ropivacaine into an intraarticular catheter placed intraoperatively followed by a continuous intraarticular infusion of ropivacaine. All patient will also receive a sustained-release oral opioid and oral rescue opioids determined by pain severity using the Visual Analog Scale (VAS)

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Elective primary knee arthroplasty
  • ASA I,II,&III patients
  • Spinal Anaesthesia

排除标准

  • Patients refusing consent
  • Contraindications to regional anaesthesia
  • Preexisting neurological disease
  • Alcohol or drug abuse
  • Inability to use the outcome assessment tools
  • Wheel chair or walker dependent
  • Pregnancy

结局指标

主要结局

Static and dynamic pain scores (VAS)

时间窗: 72 h

次要结局

  • Maximum knee flexion (active/passive)>= 90°(72 h)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Karl Trauner

M.D.

Landeskrankenhaus Feldbach

研究点 (2)

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