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Clinical Trials/NCT06436105
NCT06436105
Completed
Not Applicable

Comparison of Perioperative Analgesic Effectiveness of Patients Who Had Fasia Iliac Compartment Block and 4in1 Block Applied in Total Knee Prosthesis Surgery

Diskapi Yildirim Beyazit Education and Research Hospital1 site in 1 country60 target enrollmentMay 30, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pain, Postoperative
Sponsor
Diskapi Yildirim Beyazit Education and Research Hospital
Enrollment
60
Locations
1
Primary Endpoint
Total tramadol consumption in 24 hours (mg)
Status
Completed
Last Updated
10 months ago

Overview

Brief Summary

Patients who will undergo elective total knee arthroplasty surgery under spinal anesthesia will be included in the study according to the postoperative analgesia method applied: Group Control, Group FICB and Group 4in1. Peripheral nerve block will be performed with 30 ml %0.25 bupivacaine for Group FICB and Group 4 in 1 patients. Peripheral nerve block will not be performed on Group Control patients. Patient-controlled analgesia will be given to all three groups in the postoperative period. PCA is a pain palliation method routinely used in all patients postoperatively. NRS score, PCA tramadol consumption, PCA demand, need for additional analgesia, patient satisfaction, nausea and vomiting will be monitored 24 hours postoperatively. The aim of this study is to compare the perioperative analgesic effectiveness of patients who underwent fascia iliaca compartment block and 4 in 1 block in total knee arthroplasty surgery, with each other and with the control group.

Detailed Description

Total knee arthroplasty is a surgical procedure performed mostly on patients with osteoarthritis who have failed traditional conservative treatment. Increasing knee osteoarthritis due to reasons such as life expectancy and body mass index causes this surgical procedure to be performed more frequently. The knee joint which is innervated by the femoral, obturator, sciatic nerves and their branches has a complicated innervation and the pain following total knee arthrplasty is quite severe. It is aimed to provide effective analgesia by blocking these nerves or terminal branches with various peripheral nerve blockade methods under USG guidance. In recent years, interest in studies aiming to block these nerves with a single injection has been increasing. 4 in 1 block is a new technique applied from a single injection point to block the saphenous, obturator, sciatic and vastus medialis nerves that innervate the knee joint. Fascia iliaca compartment block is a reliable technique applied from a single injection point to block the femoral, lateral femoral cutaneous and obturator nerves behind the fascia iliaca. Patients who will undergo elective total knee arthroplasty surgery under spinal anesthesia will be included in the study according to the postoperative analgesia method applied: Group Control, Group FICB and Group 4in1. Peripheral nerve block will be performed with 30 ml %0.25 bupivacaine for Group FICB and Group 4 in 1 patients. Peripheral nerve block will not be performed on Group Control patients. Patient-controlled analgesia will be given to all three groups in the postoperative period. PCA is a pain palliation method routinely used in all patients postoperatively. NRS score, PCA tramadol consumption, PCA demand, need for additional analgesia, patient satisfaction, nausea and vomiting will be monitored 24 hours postoperatively. The aim of this study is to compare the perioperative analgesic effectiveness of patients who underwent fascia iliaca compartment block and 4 in 1 block in total knee arthroplasty surgery, with each other and with the control group.

Registry
clinicaltrials.gov
Start Date
May 30, 2024
End Date
July 8, 2024
Last Updated
10 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Diskapi Yildirim Beyazit Education and Research Hospital
Responsible Party
Principal Investigator
Principal Investigator

Savas Altinsoy

Principal Investigator

Diskapi Yildirim Beyazit Education and Research Hospital

Eligibility Criteria

Inclusion Criteria

  • With informed consent
  • Elective total knee arthroplasty with spinal anesthesia
  • Oriented and cooperative
  • ASA Classification I-II-III
  • 18-85 years old

Exclusion Criteria

  • Anticoagulant medication
  • Coagulopathy
  • Infection at the site of peripheral nerve block application
  • Allergy to local anesthetics
  • Pregnant or suspected pregnancy

Outcomes

Primary Outcomes

Total tramadol consumption in 24 hours (mg)

Time Frame: 24 hours postoperatively

Total tramadol consumption used in the first 24 hours postoperatively

Secondary Outcomes

  • Pain on the Numeric Rating Scale (NRS)(24 hours postoperatively)
  • Rescue Analgesic(24 hours postoperatively)
  • Patient satisfaction(24 hours postoperatively)

Study Sites (1)

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