Comparison of Patient-controlled Analgesia Regimenfor Postoperative Pain in Patients Undergoing Total Knee Arthroplasty
Not Applicable
Completed
- Conditions
- Postoperative Pain, Acute
- Interventions
- Registration Number
- NCT05861791
- Lead Sponsor
- Chung-Ang University Gwangmyeong Hospital
- Brief Summary
Patients who undergoing total knee arthroplasty under spinal analgesia will be recruited and randomly assigned to the following two groups according to the regimen of PCA: (A) opioid group who receive only fentanyl citrate 1200mcg for continuous infusion drug, (B) non-opioid group who receive ketorolac tromethamine 150mg with nefopam hydrochloride 100mg for continuous infusion drug. All the patients will receive additional fentanyl citrate as bolus injection drug if they need more analgesics postoperatively.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 98
Inclusion Criteria
- ASA physical status I-II
- undergoing elective total knee arthroplasty under spinal anesthesia
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Exclusion Criteria
- history of stomack ulceration
- increased ICP
- bronchial asthma
- allergy on aspirin, NSAIDs, Nefopam
- drug user of antiplatelet or anticoagulant
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description opioid group Fentanyl IV-PCA consisted of fentanyl non-opioid group ketorolac tromethamine with nefopam hydrochloride IV-PCA consisted of ketorolac and nefopam
- Primary Outcome Measures
Name Time Method postoperative pain score 24 hours after the surgery evaluated by visual analogue scale
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
ChungAng University Gwangmyeong Hospital
🇰🇷Gyeonggi-do, Gwangmyeon-si, Korea, Republic of