Het ontstaan van post trombotisch syndroom.
Completed
- Conditions
- Post thrombotic syndromeDeep venous thrombosis
- Registration Number
- NL-OMON25244
- Lead Sponsor
- Maastricht University Medical Centre
- Brief Summary
Bouman AC, Cheung YW, Spronk HM, Schalkwijk CG, ten Cate H, ten Wolde M, ten Cate-Hoek AJ. Biomarkers for post thrombotic syndrome: a case-control study. Thromb Res. 2014 Aug;134(2):369-75. doi: 10.1016/j.thromres.2014.06.010. Epub 2014 Jun 13. PubMed PMID: 24975586.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 90
Inclusion Criteria
Cases:
1. Minimum age 18 years;
Exclusion Criteria
Pre-existent venous insufficiency (skin signs C3-C6 on CEAP score or requiring ECS therapy).
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome will be the difference in levels of plasma concentrations of markers in relation to the outcome PTS between patients with PTS and patients without PTS.
- Secondary Outcome Measures
Name Time Method 1. Dose-dependent relation between the level of markers and severity of PTS;<br /><br>2. Plasma concentration of markers in healthy controls that never had a DVT, compared to patients that have had a DVT.<br>