The effects of a combination therapy of clonidine with dextromethorphan and/or amantadine on opium withdrawal syndrome compared with the single therapy of clonidine
Not Applicable
- Conditions
- Mental and behavioural disorders due to use of opioids.Mental and behavioural disorders due to use of opioids
- Registration Number
- IRCT201207196972N2
- Lead Sponsor
- Research Vice Chancellor of Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 120
Inclusion Criteria
Inclusion criteria : Male sex; Aging from 20 to 40 years;Positive morphine test; Substance abuse diagnosis according to the DSM-IV-TR criteria.
Exclusion criteria:The hepatic and renal diseases will evaluate according to the Creatinine and ALT measurements and if the subjects have levels higher than 1.2 mg/dl and 40 IU, respectively, will exclude; Also all patients will evaluate by clinical interview and the psychotic patientswill exclude.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Relieving the opioid withdrawal symptoms. Timepoint: Admission day, and 24, 48, and 72 hours later. Method of measurement: Clinical Opiate Withdrawal Scale.
- Secondary Outcome Measures
Name Time Method