Repetitive frontal home-based transcranial direct current stimulation (tDCS) als a potential treatment for long-COVID-related fatigue

Not Applicable

Recruiting

• Conditions: ong-COVID patients with cognitive fatigue; U09.9!

• Registration Number: DRKS00033161
• Lead Sponsor: Otto-von-Guericke-Universität Magdeburg, med. Fakultät, Universitätsklinik für Neurologie, Sektion Neuropsychologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-11-29
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

cognitive fatigue (WeiMUS cognitive scale >= 17)
- positive SARS-CoV-2-finding (COVID-19), at least 3 months old

Exclusion Criteria

- diagnose of depression or anxiety disorder, other psychiatric disorders
- medication with antidepressants, opioids, anticonvulsants
- neurological disorders

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement of subjective fatigue (MFIS; total and subscales) by repetitive verum tDCS<br>Assessment: Directly before to max. two days before the first stimulation (pre), one day after the last stimulation (post), one month after the last stimulation (follow-up)

Secondary Outcome Measures

Name	Time	Method
- Improvement in quality of life (EQ-5D-5L)<br>- Improvement in subjective state fatigue (VAS)<br>- Improvement of objective fatigability parameters (behavioral data)<br>- Influence on fatigability-associated EEG components: Alpha, Theta, P50<br>Assessment: Directly before or max. two days before the first stimulation (pre), one day after the last stimulation (post), one month after the last stimulation (follow-up)