Multidimensional Determinants and Structural Foundations of Functional Health In Women Aged 45-60: The Role of Muscle and Bone Health
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 200
研究概览
简要总结
The goal of this observational study is to learn about the multidimensional determinants of functional health in women aged 45 to 60 years. The study will focus on the role of muscle strength, bone mineral density, body composition, physical activity, sleep quality, depressive symptoms, and menopause-related symptoms in functional health.
The main questions it aims to answer are:
- Does muscle strength contribute to functional health in women aged 45 to 60 years?
- Does bone mineral density contribute to functional health in women aged 45 to 60 years?
- How are physical activity, sleep quality, depressive symptoms, body composition, and menopause-related quality of life associated with functional health?
Participants will:
- Undergo handgrip strength measurement
- Perform a 30-second chair stand test
- Undergo bone mineral density and body composition assessment
- Complete questionnaires about physical activity, sleep quality, depressive symptoms, menopausal symptoms, and quality of life
- Provide demographic and clinical information
详细描述
This is a single-center, cross-sectional observational study designed to evaluate the multidimensional determinants of functional health in women aged 45 to 60 years. The study will be conducted at the Department of Obstetrics and Gynecology, Kartal Dr. Lütfi Kırdar City Hospital, Istanbul, Turkey.
Midlife and the menopausal transition are associated with changes in muscle strength, bone mineral density, body composition, metabolic profile, physical performance, sleep quality, mood, and menopause-related symptoms. Functional health is a multidimensional construct encompassing physical capacity, independence in daily activities, psychological well-being, and health-related quality of life. This study will assess functional health using biological, behavioral, psychological, and symptom-related indicators rather than relying on a single test or questionnaire score.
Inclusion Criteria are:
- Women aged 45 to 60 years
- Ability to read and complete study questionnaires
- Provision of written informed consent
- Ability to complete physical performance assessments
Exclusion Criteria are:
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 45 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Women aged 45 to 60 years
- •Ability to read and complete study questionnaires
- •Provision of written informed consent
- •Ability to complete physical performance assessments
排除标准
- •Acute systemic illness
- •Active malignancy
- •Severe neurological or orthopedic impairment limiting physical performance assessment
- •Cognitive impairment precluding informed consent or questionnaire completion
研究者
Elif Unlugedik Sayin
MD, PhD
Kartal City Hospital