Association of Anemia With Hospital Costs in Elective Colorectal Surgery

Completed

• Conditions: Colon Cancer; Economic Problems; Surgical Blood Loss; Surgery; Anemia
• Interventions: Other: Anemia

• Registration Number: NCT03476707
• Lead Sponsor: Ottawa Hospital Research Institute

Brief Summary

The objective is to measure the adjusted association between preoperative anemia and total hospital costs. We hypothesize that patients with anemia before surgery will have higher hospitalization costs than people without anemia.

Detailed Description

This study will examine the association between preoperative anemia (hematocrit less than 0.39; low blood counts) and hospital total costs from elective colorectal surgery. Total costs will be defined as the combination of direct and indirect costs ascertained using standardized patient-level costing algorithms (i.e. the standard way that hospital measure their costs). Adjustment will be made for factors that are likely to influence both the presence of anemia and costs of care.

Study Timeline

• Study Start: 2010-01
• Primary Completion: 2016-12
• Status Verified: 2018-03
• Study Completion: 2018-03
• Study First Submitted: 2018-03-19
• Study First Submitted QC: 2018-03-19
• Last Update Submitted: 2018-03-23
• Study First Posted: 2018-03-26
• Last Update Posted: 2018-03-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Elective hospital admission
• having colorectal surgery

Exclusion Criteria

• not enrolled in national surgical quality improvement program data collection

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Anemic	Anemia	People with a preoperative hematocrit less than 0.39

Primary Outcome Measures

Name	Time	Method
Total Hospital Costs	Hospital admission to date of discharge from hospital, or 365 days after admission, whichever came first	Direct and indirect costs accrued during the index hospitalization. Costs were measured using standard and validated algorithms, standardized to 2016 CAD. This method accounts for a patient's resource intensity weight, their case mix group, as well as fixed patient costs (e.g., medications, investigations) and indirect costs to the hospital based on patient's location of care (intensive care unit versus ward) and length of stay.

Secondary Outcome Measures

Name	Time	Method
Length of Stay	Date of surgery to date of hospital discharge, or up to one year after surgery (whichever comes first)	Number of days in hospital after surgery
Red Blood Cell Transfusion	Hospital admission to date of surgery, or 365 days after admission, whichever came first	Any red blood cell transfusion received