EFfect of brEastfeeding on lipid profile and cardiovascular risk Markers In womeN with familial hypercholesterolemiA

• Conditions: Familial hypercholesterolemia; hereditary high cholesterol; 10027424

• Registration Number: NL-OMON56956
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

1) Women aged >= 18 years
2) Have a clinical (based on the Dutch Lipid Clinic Network score) or genetic
diagnosis of FH.
3) Pregnant.
4) Have a sufficient command of the Dutch, Norwegian or English language.

Exclusion Criteria

1) below 18 years of age.
2) Postmenopausal.
3) Use of contraception.
4) Underwent ovariectomy.
5) Not able or willing to give informed consent.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Investigate the effects of breastfeeding on lipid profile in women with FH. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Investigate the composition of breast milk of women with FH and compare between<br /><br>women with and without statin use.<br /><br>Investigate the influence of breastfeeding on other cardiovascular risk markers<br /><br>in women with FH (e.g. inflammation such as CRP).</p><br>