NCT04477733已完成4 期
Effect of Butorphanol on Colonoscopy for Patients With Postoperative Visceral Pain
Beijing Tiantan Hospital1 个研究点 分布在 1 个国家目标入组 203 人开始时间: 2020年8月14日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 203
- 试验地点
- 1
- 主要终点
- visceral pain
研究概览
简要总结
The total incidence of abdominal pain after colonoscopy is almost 50%. Butorphanol is a mixed opioid receptor agonist-antagonist, which has strong sedative and analgesic effects. This clinical study aims to explore the effectiveness and safety of butorphanol combined with propofol for colonoscopy to reduce postoperative visceral pain, and provide a basis for improving the quality of surgery and comfortable medical treatment for patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA status I-11
- •patients performing colonoscopy
- •sign the informed consent
排除标准
- •BMI>30, pregnant
- •depression
- •patients dependent on opioids
- •hypertension poorly controlled
- •serious complications of important organs
- •obvious abdominal pain before colonoscopy
研究组 & 干预措施
control group
Placebo Comparator
干预措施: Saline (Drug)
Butorphanol group
Experimental
干预措施: Butorphanol Injection (Drug)
结局指标
主要结局
visceral pain
时间窗: 10 minutes after recovery
VAS score of visceral pain
次要结局
- visceral pain at 20 and 30 minutes after recovery(20 and 30 minutes after recovery)
研究者
Ruquan Han
professor
Beijing Tiantan Hospital
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
The Analgesic Effect of Butorphanol After Cesarean SectionAnalgesiaNCT04490980Tongji Hospital100
已完成
不适用
Butorphanol in Pain Following Ablation for Hepatic TumorVisceral PainMicrowave AblationHepatic TumorNCT06031129Bibo Wang300
尚未招募
Unknown
To compare butorphanol and buprenorphine with levo-bupivacaine for post-operative analgesiaCTRI/2023/08/056741Rohilkhand Medical College And Hospital
已完成
4 期
Comparison of Butorphanol and Tramadol Associated Patient-Controlled Analgesia (PCA) After HysterectomyPostoperative PainHysterectomyNCT00510666Nanjing Medical University841
Unknown
不适用
Butorphanol Mitigate Emergence Agitation in Patients Undergoing Functional Endoscopic Sinus SurgeryAgitationNCT03398759RenJi Hospital700