布托啡诺 (Stadol)

概览

Butorphanol is an opioid agonist-antagonist used to treat moderate to severe pain.

作用机制

The exact mechanism of action is unknown, but is believed to interact with an opiate receptor site in the CNS (probably in or associated with the limbic system). The opiate antagonistic effect may result from competitive inhibition at the opiate receptor, but may also be a result of other mechanisms. Butorphanol is believed to have both partial agonism and partial antagonism at the μ-opioid receptor, as well as partial agonist and antagonist activity at the κ-opioid receptor.

适应症

For the relief of moderate to severe pain.

• Pain
• Perioperative Pain
• Severe Pain