NCT02770976已完成不适用
Respiratory Pattern During Neurally Adjusted Ventilator Assist (NAVA) in Preterm Infants
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 2
- 主要终点
- maximum Edi
研究概览
简要总结
This study is to investigate the effect of a wide range of assistance levels on respiratory pattern, breathing variability including tidal volume and peak inspiratory pressure during neurally adjusted ventilatory assist (NAVA) in preterm infants. The investigators also aim to explore whether the effects of NAVA on the electrical activity of diaphragm (Edi) signal amplitude, work of breathing and comfort of preterm infants.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •preterm infants born before 36 weeks of gestational age
- •who received mechanical ventilatory care through the endotracheal tube at least 24 hours for respiratory distress
- •no use of anesthetics or analgetics
排除标准
- •with major congenital anomalies (facial, gastrointestinal tract, cardiac, etc)
- •with phrenic nerve palsy or injuries
结局指标
主要结局
maximum Edi
时间窗: the middle 2 minutes duration out of the total interval of 10 minutes
mean of recorded maximum electrical activities in the middle 2 min duration out of the total 10 min period
次要结局
- peak inspiratory pressure(the middle 2 minutes duration out of the total interval of 10 minutes)
- tidal volume(the middle 2 minutes duration out of the total interval of 10 minutes)
- electrical time product(the middle 2 minutes duration out of the total interval of 10 minutes)
- inspiratory time in excess(the middle 2 minutes duration out of the total interval of 10 minutes)
- comfort score(the 5-min point in the total 10-min period)
研究者
研究点 (2)
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