The Effects of Neurally Adjusted Ventilatory Assist (NAVA) on Improving Patient-ventilator Interaction in Patients Undergoing Ventilation for Acute Respiratory Failure
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University Hospital, Geneva
- Enrollment
- 13
- Locations
- 7
- Primary Endpoint
- Patient-ventilator synchronization parameters
Study Overview
Brief Summary
The present study aims to compare various parameters reflecting patient-ventilator synchrony during standard pressure support (PS) and Neurally Adjusted Ventilatory assist (NAVA) in a group of patients receiving non invasive ventilation (NIV)for an episode of acute respiratory failure of various origin.
Detailed Description
The present study aims to compare various parameters reflecting patient-ventilator synchrony during standard pressure support (PS) and Neurally Adjusted Ventilatory assist (NAVA) in a group of patients receiving non invasive ventilation (NIV)for an episode of acute respiratory failure of various origin. The subgroup of COPD patients will be analyzed separately. The effects of various setting of Neurally adjusted ventilatory assist on patient-ventilator interaction will also be explored.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Supportive Care
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 90 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients admitted to the ICU and treated with Non invasive ventilation for acute respiratory failure of any origin
Exclusion Criteria
- •severe hypoxemia requiring an FIO2>0.6
- •hemodynamic instability
- •known oesophageal problem
- •active upper gastro-intestinal bleeding
- •any other contraindication to the insertion of a naso-gastric tube
- •impaired consciousness or absence of patient cooperation
- •facial or laryngeal lesions contraindicating the use of NIV
- •poor short term prognosis
Arms & Interventions
Pressure support
Non invasive ventilation under pressure support (PS)
Neurally Adjusted Ventilatory Assist
Non invasive ventilation under Neurally Adjusted ventilatory Assist
Intervention: Neurally Adjusted Ventilatory Assist (Device)
Outcomes
Primary Outcomes
Patient-ventilator synchronization parameters
Secondary Outcomes
No secondary outcomes reported
