The Effects of Neurally Adjusted Ventilatory Assist (NAVA) on Improving Patient-ventilator Interaction in Patients Undergoing Ventilation for Acute Respiratory Failure
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 13
- 试验地点
- 7
- 主要终点
- Patient-ventilator synchronization parameters
研究概览
简要总结
The present study aims to compare various parameters reflecting patient-ventilator synchrony during standard pressure support (PS) and Neurally Adjusted Ventilatory assist (NAVA) in a group of patients receiving non invasive ventilation (NIV)for an episode of acute respiratory failure of various origin.
详细描述
The present study aims to compare various parameters reflecting patient-ventilator synchrony during standard pressure support (PS) and Neurally Adjusted Ventilatory assist (NAVA) in a group of patients receiving non invasive ventilation (NIV)for an episode of acute respiratory failure of various origin. The subgroup of COPD patients will be analyzed separately. The effects of various setting of Neurally adjusted ventilatory assist on patient-ventilator interaction will also be explored.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients admitted to the ICU and treated with Non invasive ventilation for acute respiratory failure of any origin
排除标准
- •severe hypoxemia requiring an FIO2>0.6
- •hemodynamic instability
- •known oesophageal problem
- •active upper gastro-intestinal bleeding
- •any other contraindication to the insertion of a naso-gastric tube
- •impaired consciousness or absence of patient cooperation
- •facial or laryngeal lesions contraindicating the use of NIV
- •poor short term prognosis
研究组 & 干预措施
Pressure support
Non invasive ventilation under pressure support (PS)
Neurally Adjusted Ventilatory Assist
Non invasive ventilation under Neurally Adjusted ventilatory Assist
干预措施: Neurally Adjusted Ventilatory Assist (Device)
结局指标
主要结局
Patient-ventilator synchronization parameters
次要结局
未报告次要终点