NCT06228911已完成不适用
Increased Blood Glucose Levels After Steroid Injection Into Osteoarthritic Knee in Diabetic Patients' Type 2
Syrian Private University1 个研究点 分布在 1 个国家目标入组 600 人开始时间: 2020年1月15日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 600
- 试验地点
- 1
- 主要终点
- high blood glucose
研究概览
简要总结
a sample of 600 patients diagnosed as Knee osteoarthritis injected with 40 mg triamcinolone, recorded their morning fasting blood glucose levels for 7 days before injection used as the baseline blood glucose level, which was compared with FBS levels for 14 days after steroid injection. Our study compared the differences in blood glucose changes between HbA1c >7% and HbA1c ≤7% groups and those between insulin and non-insulin treated groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Factorial
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years, patients with knee osteoarthritis diagnosed according to American College of Rheumatology (ACR) Criteria (17), and grade1-3 in Kallgren-Laurence radiographic scale (18), whom failed to response to medical treatment including paracetamol and nonsteroidal anti-inflammatory medication, and to physical therapy, checking their blood glucose values daily.
排除标准
- •Patients who were unable to provide consent, patients had any contraindications to corticosteroids, patients who had received oral corticosteroid in the past 6 months or corticosteroid injection in the previous 3 months, patients who had no monitoring HbA1c level before injection or also whom had not monitor blood glucose levels before or after injection.
研究组 & 干预措施
insulin treated group
Experimental
干预措施: steroid (triamcinolone) (Drug)
non-insulin treated groups
Experimental
干预措施: steroid (triamcinolone) (Drug)
结局指标
主要结局
high blood glucose
时间窗: 3 years
glucose increases after steroid dose
low blood glucose
时间窗: 3 years
glucose decreases after steroid dose
次要结局
未报告次要终点
研究者
Diaa Haj Ali
Medical Doctor Diaa Haj Ali
Syrian Private University
研究点 (1)
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