ycopene improves clinical and reduces harmful radicals in Oral submucous fibrosis patients
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Patients suffering from OSMF were includedAll the patients showed decreased signs and symptomsSalivary oxidative stress was reduced too
- Registration Number
- CTRI/2017/08/009488
- Lead Sponsor
- Self
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
patients with clinically diagnosed oral submucous fibrosis
Exclusion Criteria
1. Patient on any medications for OSMF
2. Patient with any other apparent systemic disease
3. Patient with other oral potentially malignant disorders
4. Patient with any oral malignant changes.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Increased oxidative stress in OSMF prior to treatment i.e. Pretreatment increased salivary malondialdehyde and decreased superoxide dismutase. <br/ ><br>Decreased oxidative stress after therapy i.e. post treatment decreased salivary malondialdehyde and increased superoxide dismutase.Timepoint: After 2 months
- Secondary Outcome Measures
Name Time Method Decreased clinical signs and symptoms after therapy with lycopene viz., mouth opening, burning sensation, tongue protrusionTimepoint: after 2 months