Comparison of Breathing Pattern During PSV and NAVA
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 10
- Locations
- 2
- Primary Endpoint
- Comparison of breathing pattern during pressure support and Neurally Adjusted Ventilatory Assist (NAVA)
Study Overview
Brief Summary
Comparison of Breathing pattern during mechanical ventilation. Two modes of mechanical ventilation are compared (Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist)
Detailed Description
Eligibility : healthy subject without respiratory complications in the past
Subjects will breath spontaneously without mechanical ventilation, with Pressure Support Ventilation and with Neurally Adjusted Ventilatory Assist during.
Three levels of pressurisation will be tested : 5 cmH2O, 8 cmH2O and 12 cmH2O Duration of each condition will be about 15 minutes.
Measurements will include:Flow, airway pressure, SaO2, PtCO2, diaphragmatic electromyography, chest wall motion by optoelectronic plethysmography
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Basic Science
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Age > 18 years
- •Healthy Subject without any chronic disease
Exclusion Criteria
- •Absence of consent
Outcomes
Primary Outcomes
Comparison of breathing pattern during pressure support and Neurally Adjusted Ventilatory Assist (NAVA)
Time Frame: 2h
Secondary Outcomes
- Tidal volume evaluated by optoelectronic plethysmography(2h)
- Electrical diaphragmatic activity recorded by mechanical ventilator(2h)
Investigators
Lofaso
MD-PhD
Centre d'Investigation Clinique et Technologique 805