Comparison of Positive Pressure Ventilation Strategies in Young Children Undergoing Laparoscopic Inguinal Hernia Repair With Laryngeal Mask Airway: A Prospective Randomized Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 78
- 试验地点
- 1
- 主要终点
- (PIP)
研究概览
简要总结
The most basic modes of mechanical ventilation are volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV). VCV guarantees a target volume of ventilation using a constant flow, but may lead to high peak airway pressure (Ppeak) during the gas insufflation . In PCV mode, on the other hand,
详细描述
The laryngeal mask airway (LMA) provides a useful alternative for airway management during general anaesthesia. Inflation of the LMA cuff produces a low-pressure seal around the larynx, enabling positive pressure ventilation (PPV). The use of LMA as an airway management technique is common in the pediatric anesthesia because of its less irritating effect on the airways due to its location in the upper larynx. Now, the use of laryngeal mask instead of tracheal intubation for airway management has been achieved in day surgery, therefore, how to perform a respiratory management with a laryngeal mask is particularly important. In addition, mechanical ventilation is also a commonly used method of airway management in clinical practice. the ventilator will deliver a constant pressure by decelerating the flow. However, the ventilation volume varies according to the patient's respiratory mechanics . Pressure-controlled ventilation-volume guaranteed (PCV-VG) combines the advantages of both VCV and PCV, which delivers a stable ventilation volume using a decelerating flow pattern.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Sequential
- 主要目的
- Other
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 1 Year 至 5 Years(Child)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age between 1 and 5 years.
- •patient scheduled for laparoscopic inguinal hernia repair.
- •American Society of Anesthesiologists classification of physical status of I-II.
排除标准
- •cardiopulmonary disease.
- •severe hepatorenal dysfunction.
- •history of upper respiratory tract infection 2 weeks before the operation.
- •overweight [more than 20% of standard body weight].
- •neuromuscular disease.
- •anticipated difficult airway.
- •hiatus hernia or gastroesophageal reflux disease.
结局指标
主要结局
(PIP)
时间窗: within one hour
peak inspiratory pressure
Pplat
时间窗: within one hour
plateau airway pressure
(Cdyn)
时间窗: within one hour
pulmonary dynamic compliance
(RAW
时间窗: within one hour
airway resistance
VT
时间窗: within one hour
exhaled tidal volume
EtCO2
时间窗: within one hour
end-expiratory carbon dioxide
Vd/VT
时间窗: within one hour
physiologic dead space over tidal volume
次要结局
- (MAP)(within one hour)
- (HR)(within one hour)
- postoperative respiratory adverse events(within 24 hour)
研究者
Mariana Soliman
egypt benisuef
Beni-Suef University
