Comparison of Volume- and Pressure- Controlled Ventilation With Laryngeal Mask Airway Guardian in Obese Patients Undergoing Laparoscopic Gynecologic Surgery-A Perspective, Randomized, Blind Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Gynecologic Disease
- Sponsor
- Haiyun Wang
- Enrollment
- 40
- Primary Endpoint
- peak pressure
- Last Updated
- 12 years ago
Overview
Brief Summary
The purpose of this study is to compare volume- and pressure- controlled ventilation with laryngeal mask airway Guardian in obese patients undergoing laparoscopic gynecologic surgery in terms of ventilatory efficacy, airway leak pressure (airway protection), ease-of-use and complications.
Detailed Description
The Guardian Laryngeal Mask (Ultimate Medical Pty Ltd, Richmond, Vic, Australia) is a new silicone-based single-use extraglottic airway device that forms a seal with the glottis for ventilation and with the hypopharynx for airway protection, and provides a gastric drainage port. The aim of the following perspective, randomized, blind trial study id to compare how the volume-controlled ventilation and pressure-controlled ventilation modes using the Laryngeal Mask Guardian affect the pulmonary mechanics, the gas exchange and the cardiovascular responses particularly in obese patients undergoing gynecological laparoscopy.
Investigators
Haiyun Wang
M.D., Ph.D.
Tianjin Medical University General Hospital
Eligibility Criteria
Inclusion Criteria
- •Ambulatory patients scheduled to undergo laparoscopic gynecologic surgery under a short general paralysed anesthesia of less than 2 hours (ASA physical status I-II)
- •18 to 65 years of age
- •A body mass index \<40 kg • m-2
Exclusion Criteria
- •Difficult airway
- •Recent history of upper respiratory tract infection and sore throats
- •A history of esophageal reflux disease
- •Kinesia patients
- •Inability to understand the Study Information Sheet and provide a written consent to take part in the study
Outcomes
Primary Outcomes
peak pressure
Time Frame: 5 min
The end-tidal carbon dioxide, the peak pressure, the mean airway pressure, the compliance were continuously monitored during the procedure and they were recorded at T1:just before carbon dioxide insufflation, T2: 30 minutes after carbon dioxide insufflation and T3: 10 minutes after the withdrawal of carbon dioxide. Data on gas exchange (pH、PaCO2、PaO2 ) at T1、T2 and T3 were recorded by artery blood gas analysis.
Secondary Outcomes
- Blood pressure(intraoperative)
- heart rate(intraoperative)