Comparison of Volume Controlled Ventilation and Pressure Controlled Ventilation in Laparoscopic Bariatric Surgery
- Conditions
- Bariatric Surgery
- Registration Number
- NCT03758937
- Lead Sponsor
- Antalya Training and Research Hospital
- Brief Summary
The purpose of this study is to compare volume controlled-ventilation (VCV) and pressure-controlled ventilation (PCV) in terms of pulmonary gas exchange, respiratory mechanics and arterial blood gas values in patients undergoing laparoscopic bariatric surgery.
- Detailed Description
Today, morbid obesity has become a global problem. It is not clear which mechanical ventilation mode will be used in bariatric surgery, which is one of the treatment options of these patients. VCV is the most commonly used mode to ventilate anesthetized patients. However, especially in obese patients, high airway pressures and hypoxia may occur due to increased intrapulmonary shunts. Therefore, we aimed to investigate the potential of PCV strategy to improve pulmonary gas exchange, respiratory mechanics and arterial blood gas values according to VCV in patients undergoing bariatric surgery.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 62
- 18 years or above,
- ASA II patients
- BMI > 40 kg / m2
- No serious comorbidity.
- Unstable patients during the operation
- The requirement for mechanical ventilation in the postoperative period.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Partial oxygen pressure through surgery completion, an average of 90 minutes Assessed through surgery completion, an average of 90 minutes by using arterial blood gas
- Secondary Outcome Measures
Name Time Method Peak airway pressure 5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes Assessed 5 minutes after induction, 30 minutes after pneumoperitoneum and through surgery completion, an average of 90 minutes by using the patient monitor.
Dynamic compliance 5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes Assessed 5 minutes after induction, 30 minutes after pneumoperitoneum and through surgery completion, an average of 90 minutes by using formula (Tidal volume/peak airway pressure - Positive end-expiratory pressure)
Inspired oxygen pressure / Fractional oxygen ratio 5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes Assessed 5 minutes after induction, 30 minutes after pneumoperitoneum and through surgery completion, an average of 90 minutes
Alveolar-arterial oxygen gradient pressure 5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes Assessed 5 minutes after induction, 30 minutes after pneumoperitoneum and through surgery completion, an average of 90 minutes by using formula (D(A-a) O2).
Partial carbon dioxide pressure 5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes Assessed 5 minutes after induction, 30 minutes after pneumoperitoneum and through surgery completion, an average of 90 minutes by using arterial blood gas analysis.
Partial carbon dioxide pressure - end-tidal carbon dioxide pressure 5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes Assessed 5 minutes after induction, 30 minutes after pneumoperitoneum and through surgery completion, an average of 90 minutes by using arterial blood gas analysis and end-tidal monitor.
Trial Locations
- Locations (1)
Antalya Traning and Research Hospital
🇹🇷Antalya, Turkey
Antalya Traning and Research Hospital🇹🇷Antalya, Turkey