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Clinical Trials/NCT03758937
NCT03758937
Completed
Not Applicable

Comparison of Volume Controlled Ventilation and Pressure Controlled Ventilation in Terms of Respiratory Mechanics in Laparoscopic Bariatric Surgery

Antalya Training and Research Hospital1 site in 1 country62 target enrollmentApril 1, 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Bariatric Surgery
Sponsor
Antalya Training and Research Hospital
Enrollment
62
Locations
1
Primary Endpoint
Partial oxygen pressure
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

The purpose of this study is to compare volume controlled-ventilation (VCV) and pressure-controlled ventilation (PCV) in terms of pulmonary gas exchange, respiratory mechanics and arterial blood gas values in patients undergoing laparoscopic bariatric surgery.

Detailed Description

Today, morbid obesity has become a global problem. It is not clear which mechanical ventilation mode will be used in bariatric surgery, which is one of the treatment options of these patients. VCV is the most commonly used mode to ventilate anesthetized patients. However, especially in obese patients, high airway pressures and hypoxia may occur due to increased intrapulmonary shunts. Therefore, we aimed to investigate the potential of PCV strategy to improve pulmonary gas exchange, respiratory mechanics and arterial blood gas values according to VCV in patients undergoing bariatric surgery.

Registry
clinicaltrials.gov
Start Date
April 1, 2016
End Date
August 1, 2017
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Antalya Training and Research Hospital
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • 18 years or above,
  • ASA II patients
  • BMI \> 40 kg / m2
  • No serious comorbidity.

Exclusion Criteria

  • Unstable patients during the operation
  • The requirement for mechanical ventilation in the postoperative period.

Outcomes

Primary Outcomes

Partial oxygen pressure

Time Frame: through surgery completion, an average of 90 minutes

Assessed through surgery completion, an average of 90 minutes by using arterial blood gas

Secondary Outcomes

  • Peak airway pressure(5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes)
  • Dynamic compliance(5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes)
  • Inspired oxygen pressure / Fractional oxygen ratio(5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes)
  • Alveolar-arterial oxygen gradient pressure(5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes)
  • Partial carbon dioxide pressure(5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes)
  • Partial carbon dioxide pressure - end-tidal carbon dioxide pressure(5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes)

Study Sites (1)

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