Comparison of Volume Controlled Ventilation With 1:1 Inspiratory to Expiratory Ratio and Autoflow-volume Controlled Ventilation in Robot-assisted Laparoscopic Radical Prostatectomy With Steep Trendelenburg Position and Pneumoperitoneum
Not Applicable
Completed
- Conditions
- Robot Assisted Laparoscopic Prostatectomy
- Registration Number
- NCT03202953
- Lead Sponsor
- Yonsei University
- Brief Summary
The purpose of this study is to compare the 1: 1 I: E ratio VCV and the autoflow VCV in patients undergoing robot assisted laparoscopic prostatectomy
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 78
Inclusion Criteria
- adult (20-80 years old)
- patients undergoing robot assisted laparoscopic prostatectomy
Exclusion Criteria
- history of COPD
- decreased heart function (EF <50%)
- BMI>30
- patients who cannot read the consent form (e.g., blind, foreigner)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method PaO2 30 minutes after trendelenburg position PaO2 analyzed by arterial blood gas analysis
- Secondary Outcome Measures
Name Time Method Arterial blood gas analysis 10 minutes after induction (T1), 30 minutes after trendelenburg position (T2), 60 minutes after trendelenburg position (T3), 10 minutes after supine position (T4) pH, SaO2, Base excess
PaO2 10 minutes after induction (T1), 30 minutes after trendelenburg position (T2), 60 minutes after trendelenburg position (T3), 10 minutes after supine position (T4) End tidal CO2 10 minutes after induction (T1), 30 minutes after trendelenburg position (T2), 60 minutes after trendelenburg position (T3), 10 minutes after supine position (T4) peak airway pressure 10 minutes after induction (T1), 30 minutes after trendelenburg position (T2), 60 minutes after trendelenburg position (T3), 10 minutes after supine position (T4) blood pressure 10 minutes after induction (T1), 30 minutes after trendelenburg position (T2), 60 minutes after trendelenburg position (T3), 10 minutes after supine position (T4)
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms of Volume Controlled Ventilation in robotic surgery?
How does Autoflow-volume controlled ventilation compare to standard ventilation in laparoscopic prostatectomy?
What biomarkers predict optimal ventilation strategies in Trendelenburg position surgeries?
What adverse events are associated with 1:1 I:E ratio VCV in pneumoperitoneum procedures?
Are there alternative ventilation methods for robotic prostatectomy besides VCV and Autoflow?
Trial Locations
- Locations (1)
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine
🇰🇷Seoul, Korea, Republic of
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine🇰🇷Seoul, Korea, Republic of