Comparison of Volume Controlled Ventilation(VCV) vs Autoflow-volume Controlled Ventilation(Autoflow-VCV) During Robot-assisted Laparoscopic Radical Prostatectomy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Prostate Cancer
- Sponsor
- Korea University Anam Hospital
- Primary Endpoint
- Airway pressure
- Status
- Withdrawn
- Last Updated
- 10 years ago
Overview
Brief Summary
Volume controlled ventilation(VCV) is a most common used ventilation mode during general anesthesia. But VCV can cause high airway peak pressure when patient under steep Trendelenberg position with pneumoperitoneum. Autoflow-VCV can reduce airway peak pressure and improve dynamic compliance. We will compare parameters(arterial blood gas analysis, airway compliance, etc) when each group applied VCV and autoflow-VCV during RALP.
Detailed Description
Robot assisted laparoscopic radical prostatectomy(RALP) has been used to treatment of prostate cancer since 2001. RALP offers some advantage such as reduced blood loss, sparing nerves, less postoperative pain. However, RALP require steep Trendelenberg position with pneumoperitoneum. It can cause increased airway peak pressure and unwanted hemodynamic effect under conventional volume controlled ventilation(VCV). Autoflow-VCV use decelerating flow, can reduce airway peak pressure and improve dynamic compliance. We will compare parameters(arterial blood gas analysis, airway compliance, etc) when each group applied VCV and autoflow-VCV during RALP.
Investigators
Hye-Won Shin
Director, MD, PhD
Korea University Anam Hospital
Eligibility Criteria
Inclusion Criteria
- •Adult (age 19-65)
- •American Society of Anesthesiology Classification I-III
Exclusion Criteria
- •cardiovascular disease, cerebrovascular disease, pulmonary disease
- •over BMI 30
Outcomes
Primary Outcomes
Airway pressure
Time Frame: 4hours
Airway pressure will be measured under specified ventilation mode.
Secondary Outcomes
- Vital sign(4hours)