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Clinical Trials/NCT05690867
NCT05690867
Completed
Not Applicable

Comparison of Pressure and Volume Controlled Ventilation in Terms of Mechanical Power in Upper Abdominal Surgery

Istanbul University1 site in 1 country60 target enrollmentSeptember 5, 2022
ConditionsVentilator Lung

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Ventilator Lung
Sponsor
Istanbul University
Enrollment
60
Locations
1
Primary Endpoint
calculation of mechanical power changes in two different ventilation modes
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Comparison of mechanical powers produced at volume controlled and pressure controlled mechanical ventilation

Detailed Description

The mechanical power created by mechanical ventilation, as a new concept, can enable to evaluate the effect of different components in the lung.Our aim in this study is to calculate mechanical power in different ventilation modes ( pressure controlled and volume controlled ventilation) and to compare them. To calculate the mechanical powers we will use Van der Meijden's mechanical power formula for pressure controlled ventilation and for volume controlled ventilation we will use Gattinoni's mechanical power formula. In the literature we haven't seen any publication comparing the mechanical power of two commonly used ventilation modes (volume controlled and pressure controlled ventilation)

Registry
clinicaltrials.gov
Start Date
September 5, 2022
End Date
December 5, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Reyhan Nil Kırsan

Principal Investigator

Istanbul University

Eligibility Criteria

Inclusion Criteria

  • ASA1-2 , \>18 years old patients having upper abdominal surgery

Exclusion Criteria

  • chronic obstructive lung disease, interstitial lung disease
  • chronic renal failure
  • Child-Pugh \> 6 liver disease
  • Patients who don't give consent
  • NYHA \> 2 heart failure

Outcomes

Primary Outcomes

calculation of mechanical power changes in two different ventilation modes

Time Frame: change from at the beginning of surgery till the end of surgery

mechanical power will be calculated using the Van der Meijden's formula for pressure support ventilation and Gattinoni's formula for volume controlled ventilation and two mechanical powers will be compared

Secondary Outcomes

  • hospitalisation time(up to 20 days)
  • postoperative pulmonary complications(post-operative 7 days)

Study Sites (1)

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