The effect of morphine and different local anesthetics on human chondrocytes: an in vivo study.
- Conditions
- Patients undergoing total knee arthroplasty.MedDRA version: 14.0Level: LLTClassification code 10024760Term: Local anestheticSystem Organ Class: 10042613 - Surgical and medical proceduresTherapeutic area: Body processes [G] - Cell Physiological Phenomena [G04]
- Registration Number
- EUCTR2011-004989-16-BE
- Lead Sponsor
- Ghent University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- Not specified
• Adult = 18 years = 90 years old
• Able to comprehend, sign and date the written informed consent document to participate in the clinical trial
• Scheduled for total knee arthroplasty
• ASA Class I, II or III as assigned by the anesthesiologist
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 50
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 50
• Allergy or inability to tolerate one of the medications used in this study (cfr. 6.2) or other medications used during general anesthesia
• Weight less than 50 kilograms
• Women with childbearing potential not using contraception
• Pregnant and nursing women
• Participation in a clinical trial within the past 30 days
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method