EUCTR2008-000490-37-IT
Active, not recruiting
Phase 1
Pharmacological treatment with memantine of oscilloscopy in patients suffering from multiple sclerosis: randomized,double blind placebo controlled study. - ND
OSPEDALE S. RAFFAELE0 sites40 target enrollmentStarted: March 20, 2008Last updated:
DrugsEBIXA
Overview
- Phase
- Phase 1
- Status
- Active, not recruiting
- Sponsor
- OSPEDALE S. RAFFAELE
- Enrollment
- 40
Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional clinical trial of medicinal product
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •male or female aged 18\-60 yrs
- •diagnosis of Multiple Sclerosis (any course of disease)
- •presence of nystagmus associated with oscillopsy (as reported by the patient)
- •no MS relapse within the last 3 months and/or deterioration of \>1\.0 at EDSS scale in the last 6 months prior to enrolment
- •Oscillopsy is present at least for 25% of daytime as assessed with specific ordinal questionary for patients
- •Visual Acuity greater than 2/10 in the worst eye
- •Patients have signed the informed consent form to participate the study
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
Exclusion Criteria
- •current treatment with GABAergic drugs from at least 30 days prior to baseline visit
- •involvement in any other experimental pharmacological treatment in the previous 3 months
- •clinical history of epilepsy, Coronaric Heart Disease, pregnancy, uncontrolled hypertension, moderate renal failure
Investigators
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