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Clinical Trials/NCT02633072
NCT02633072
Completed
Phase 4

Evaluation of the Visual Acuity After the Implantation of a Tecnis +2.75 Diopters Bifocal Intraocular Lens (Tecnis ZKB00) in the Distance Dominant Eye, in Combination With a +3.25 Diopters Tecnis Bifocal Intraocular Lens (Tecnis ZLB00) in the Fellow Eye.

PD Dr. med. Eckart Bertelmann1 site in 1 country15 target enrollmentSeptember 2014
ConditionsCataract

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Cataract
Sponsor
PD Dr. med. Eckart Bertelmann
Enrollment
15
Locations
1
Primary Endpoint
Visual acuities in the far, intermediate and near
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

The objective of this study is to assess the visual outcome after the combined binocular implantation of +2.75 D and +3.25 D full-diffractive multifocal intraocular lenses.

Detailed Description

Bifocal multifocal intraocular lenses (MIOL) are effective in achieving good uncorrected visual acuities in the distance and the near. However, the intermediate vision is of increasing relevance for everyday's life. Several multifocal intraocular lenses have been developed to improvement intermediate vision. Nonetheless, those systems still possess adverse photic effects and do not garantuee spectacle independence. Therefore, the combination of a lower-addition bifocal intraocular lense in the distance-dominant eye with a higher-addition bifocal intraocular lense in the fellow-eye might be a promising approach to address these drawbacks of current binocular and trifocal intraocular lenses.

Registry
clinicaltrials.gov
Start Date
September 2014
End Date
December 2016
Last Updated
8 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
PD Dr. med. Eckart Bertelmann
Responsible Party
Sponsor Investigator
Principal Investigator

PD Dr. med. Eckart Bertelmann

Senior Consultant

Charite University, Berlin, Germany

Eligibility Criteria

Inclusion Criteria

  • clinically significant cataract
  • endothelial cell count: patients aged 18-75 years: \> 1000 cells/mm2; patients \> 75 years: \> 750 cells/mm2
  • absence of vision-limiting corneal or retinal comorbidities
  • capability to understand the informed consent

Exclusion Criteria

  • expected postoperative astigmatism \> 0.75 diopters
  • irregular astigmatism
  • dilated pupil diameter \< 3 mm
  • corneal and fundus abnormalities that might cause visual impairments
  • inability to attend follow-up visits

Outcomes

Primary Outcomes

Visual acuities in the far, intermediate and near

Time Frame: 3 months

Visual acuities are tested under photopic conditions at 5 m, intermediate (80 cm) and patient-preferred near distance (≈ 40 cm).

Mesopic vision

Time Frame: 3 months

Mesopic visual acuities are tested under high-contrast, low-contrast and low-contrast with glare.

Scotopic contrast sensitivity

Time Frame: 3 months

Scotopic contrast sensitivity are tested at 0.1 cd/m2, 0.032 cd/m2 and 0.1 cd/m2 with glare.

Secondary Outcomes

  • Spectacle independence in the far, intermediate and near(3 months)

Study Sites (1)

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