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Efficacy of Milrinone Plus Sildenafil in the Treatment of Neonates with Persistent Pulmonary Hypertensio

Not Applicable
Conditions
Respiratory
Paediatrics
Registration Number
PACTR201902691230243
Lead Sponsor
Department of Pediatrics Faculty of Medicine University of Alexandria
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
60
Inclusion Criteria

All newborn cases diagnosed with persistent pulmonary hypertension of the newborn by echocardiography that had been admitted in neonatal intensive care unit of Alexandria University Children's Hospital.

Exclusion Criteria

Neonates with any congenital heart disease.
Neonates with congenital diaphragmatic hernia.
Neonates with major surgical interventions.
Neonates with congenital lung anomalies.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Improvement of pulmonary artery systolic pressure (PASP) by echo
Secondary Outcome Measures
NameTimeMethod
Clinical improvement and fate
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