Changes in blood flow to front part of brain in recently treated patients with alcohol abuse and their association with motivation to quit.

Not Applicable

• Conditions: Health Condition 1: F10-F19- Mental and behavioral disorders due to psychoactive substance use

• Registration Number: CTRI/2018/09/015613
• Lead Sponsor: JIPMER

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Men above 18 years of age, with alcohol dependence syndrome as per international classification of diseases (ICD-10), who have undergone de-toxification therapy for approximately 2 weeks as defined by Clinical Institute Withdrawal Assessment for Alcoholâ??Revised (CIWA-Ar) < 8.

Exclusion Criteria

- Patients with organic brain disorders like epilepsy, stroke, CNS infections, CNS tumors, dementia, significant head injury, recent episode of seizure less than 48 hours before study, Diabetic vasculopathy, severe chronic kidney disease, Liver failure (as defined by the following laboratory cut offs) -S. Bilirubin > 2 mg/dl, AST/ALT > 5 times

- Substance abuse other than nicotine

- Patients with severe mental illness like psychosis, schizophrenia, manic-depressive illness.

- Patients who cannot co-operate for scan or who refuse consent for the study.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Presence or absence of regional cerebral blood flow in frontal lobes on Tc-99m ECD SPECT-CT.Timepoint: SPECT/CT acquired before subjecting patient to battery of tests on the same day. data analysed after completion of study.

Secondary Outcome Measures

Name	Time	Method
ilTimepoint: Nil