The effect of a high protein high glycaemic index meal on metabolic health markers in post-menopausal women aged between 55-70 years old.
Not Applicable
Active, not recruiting
- Conditions
- Metabolic SyndromeMetabolic and Endocrine - DiabetesMetabolic and Endocrine - Metabolic disorders
- Registration Number
- ACTRN12615001108505
- Lead Sponsor
- Auckland Uniservices
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- Female
- Target Recruitment
- 40
Inclusion Criteria
Female, postmenopausal, BMI 18-34
Exclusion Criteria
BMI outside of the range 18-34. History of cancer or heart disease or exisiting diagnosis of diabetes
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Identification of metabolites through the use of mass spectrometry seperation and detection to chemically characterise in breath and blood. There is no metabolites being specifically analysed as this an discovery study. The aim is to see a difference between healthy and Metabolic Syndrome women. [Blood samples will be taken at baseline and every 30 minutes for 5 hours post meal at each visit.<br>Breath samples will be collected by expiring gas for 20 minutes at baseline, 2 hours post meal consumption and 4 hours post meal consumption.]
- Secondary Outcome Measures
Name Time Method Hormone status including sex steroids (estrogen, testosterone, cortisol), metabolic hormones (insulin) and bone markers (C-telopeptide of type I collagen (CTX-1), vitamin D, Parathyroid hormone) will be measure to accurately profile metabolic health and response to meals. This a composite secondary outcome as each outcome will be brought together to give a full metabolic profile.[Blood samples will be taken at baseline and every 30 minutes for 5 hours post meal at each visit.]