Efficacy of modified doses of varenicline on quitting smoking attempts in Townsville, Australia

Phase 4

Withdrawn

• Conditions: Smoker; Mental Health - Addiction

• Registration Number: ACTRN12616000802404
• Lead Sponsor: Aaron Drovandi

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-06-20
• Last Update Posted: 21 February 2022

Recruitment & Eligibility

• Status: Withdrawn
• Sex: All
• Target Recruitment: 201

Inclusion Criteria

Smokers motivated to quit smoking.
Over 18 years old.
Able to attend multiple visits with a researcher in Townsville.
Smoke more than 10 Cigarettes per day.
Able to refrain from using any other smoking cessation medication, and any alternative form of tobacco during the study period.

Exclusion Criteria

Is pregnant, breastfeeding, or planning to become pregnant during the study.
Has a recent history of unstable cardiovascular or psychiatric conditions (stability is considered as having had no medication changes or condition deterioration in the past 6 months).
Has a history of a suicide attempt, and or suicidal behaviour in the previous 2 years.
Has an alcohol or other substance abuse disorder.
Has a personal history of a psychosis (schizophrenia, post-traumatic stress disorder, or bipolar disorder).
Has recently used varenicline (in the past 6 months).
Is taking any of the following medications; Naltrexone, Insulin, Nortriptyline, Clonidine, theophylline, warfarin, anorexic agents, or steroids (inhaled, or short term oral corticosteroids are permitted).

Study & Design

• Study Type: Interventional
• Study Design: Not specified