Financial decision-making in patients with neurodegenerative disorders - a pilot study.

Recruiting

• Conditions: Neurodegenerative disorders; dementia; 10057167

• Registration Number: NL-OMON50611
• Lead Sponsor: Rijksuniversiteit Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

Patients must be diagnosed with Alzheimer's Disease (AD), Mild Cognitive
Impairment (MCI) or Parkinson's disease (PD) by an experienced neurologist
according to published criteria:
1. Patients with probable AD dementia according to the criteria of The National
Institute on Aging and the Alzheimer*s Association (McKhann et al., 2011).
­1a. Only patients in the early stages of the disease (i.e. within two years
after diagnosis) will be included, since in the later stages of disease the
understanding of test instructions might be questioned.
2. Patients with amnestic MCI (single and multi-domain) according to the
criteria of The National Institute on Aging and the Alzheimer*s Association
(Albert et al., 2011).
3. Patients with idiopathic PD according to the UK Parkinson*s Disease Society
Brain Bank Criteria (Hughes, Daniel, Kilford, & Lees, 1992).
­3a. Only patients in the early stages of the disease (i.e. within five years
after diagnosis) will be included, since in the later stages of disease the
understanding of test instructions might be questioned., In case of medication
use, patients and healthy controls must be on a stable dosage of medication for
at least one month.

Exclusion Criteria

1. Presence of a neurological central nervous system disorders other than AD,
MCI or PD.
2. Surgical treatment for idiopathic PD, such as deep brain stimulation.
3. Other significant co-morbidity which might have an influence on cognition:
3a. Cardiovascular diseases, including severe hypertension.
3b. Cardiovascular risk factors, such as diabetes.
3c. Clinically evident psychological / psychiatric disorders, such as
depression, anxiety, apathy and fatigue.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary parameters of this study are the performances of patients with AD,<br /><br>MCI and PD on FDM tasks compared to healthy controls. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary parameters of this study are the performances of patients with<br /><br>AD, MCI and PD on standard neuropsychological tasks.</p><br>