A study to find out the effect of holding breaths on the Sonography (actual imaging technique) of heart in patients on breathing machine (ventilator)
Not Applicable
- Conditions
- Health Condition 1: J962- Acute and chronic respiratory failureHealth Condition 2: I999- Unspecified disorder of circulatory system
- Registration Number
- CTRI/2018/12/016721
- Lead Sponsor
- Tata Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)Adult patients ( >18 year old)
2)Patients receiving controlled mechanical ventilation while receiving sedation ± paralysis
3)Poor acoustic window for apical four chamber or parasternal short axis or both views as judged by treating doctor during point of care ultrasound/ echocardiography examination.
Exclusion Criteria
1)Patients triggering breath while on ventilator.
2)Patients on pressure support mode (or any other spontaneous mode) of ventilation
3)Prone position ventilation
4)Patients getting >6 ml kg tidal volume.
5)Expiratory flow limitation as judged by incomplete expiration on flow time scalar.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber of patients with at least one point increment in worst image quality score.Timepoint: At 8 seconds end-expiratory hold
- Secondary Outcome Measures
Name Time Method 1.Change in Carotid Doppler peak velocity (CDPV) with 8 second end expiratory hold. <br/ ><br>2.Change in IVC diameter with 8 second end expiratory hold <br/ ><br>3.Auto-PEEP in cm H2O as measured on ventilator after 8 seconds of expiratory hold. <br/ ><br>Timepoint: At 8 seconds end-expiratory hold;Predefined subgroup: <br/ ><br>Effect of end-exploratory hold will be compared in following pre-defined subgroups <br/ ><br>1.Cyclic interference in acoustic window during tidal ventilation, defined as â?¥ 1 point change in Worst image quality during tidal ventilation. <br/ ><br>Timepoint: At 8 seconds end-expiratory hold