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Clinical Trials/NCT03833037
NCT03833037
Completed
Not Applicable

Observational, Descriptive and Retrospective Study of a Cohort of 90 Consecutive Cases of Synovial Sarcoma Treated in the Orthopedic Surgery Unit of the Orthopedic Surgery and Traumatology Department of the Hospital de Sant Pau Between the Years 1983 and 2016 ( 35 Years)

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau1 site in 1 country102 target enrollmentFebruary 1, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Soft Tissue Sarcoma Adult
Sponsor
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Enrollment
102
Locations
1
Primary Endpoint
Number of cases of synovial sarcoma
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The main objectives of this study are the following: to describe the prognostic factors of survival of synovial sarcoma in patients treated by the orthopedic surgery unit oncologic of the orthopedic surgery and traumatology service of the Hospital de Sant Pau during the years 1983-2016.

Detailed Description

Another objectives of this Study are: To analyze exhaustively a series of cases of synovial sarcoma (as an example of classic subtype of soft tissue sarcoma) to analyse the complementary tests performed and their evolution over time. To analyse the results of surgical treatment and adjuvant therapies in synovial sarcoma and its evolution over time. To study the prognostic factors dependent on the patient and the applied therapeutics. To establish a results-based treatment and follow-up algorithm for patients diagnosed with synovial sarcoma. To describe the epidemiological characteristics of the group of patients in the study. To evaluate the overall survival and disease-free survival as well as the mortality of the disease. To assess the rate of local recurrence and remote dissemination of synovial sarcomas in the series. To demonstrate the influence of neoadjuvant chemotherapy and radiotherapy in the treatment of the tumor. Conduct a study by age group with respect to the influence on patient survival. To carry out a study by tumor-sized groups with respect to the influence on the survival of the patients. To carry out a chronological study on the influence of the advances in the treatments on the survival of the patients. Compare the results obtained with the published literature.

Registry
clinicaltrials.gov
Start Date
February 1, 2019
End Date
December 31, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • The inclusion criteria were: diagnosed cases of synovial sarcoma by the service of pathological anatomy and treated by unit orthopedic surgery oncology, in location of limbs, paravertebral trunk and/or pelvis. We studied the complete medical history of the cases available for the analysis and with a minimum follow-up of 12 months.

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Number of cases of synovial sarcoma

Time Frame: Two years

Study Sites (1)

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