Effects of Inulin on Satiety and Food Intake

Not Applicable

Completed

• Conditions: Obesity

• Registration Number: NCT01025375
• Lead Sponsor: Maastricht University Medical Center

Brief Summary

To assess the effect of inulin on appetite profile ratings, food intake and satiety hormones.

Detailed Description

Based upon a slower digestion and the fermentation in the intestinal tract, food containing soluble dietary fibres, such as inulin, is hypothesized to be more satiating, and to limit energy intake, in humans. Does supplementation of inulin (at 2 dosages) versus placebo over 13 consecutive days in normal to overweight men and women, lead to an increase in satiety, a reduction in food intake and stronger postprandial increases in GLP-1 and PYY?

Study Timeline

• Study Start: 2009-01
• Study First Submitted: 2009-12-02
• Study First Submitted QC: 2009-12-02
• Study First Posted: 2009-12-03
• Primary Completion: 2010-02
• Study Completion: 2010-02
• Status Verified: 2012-08
• Last Update Submitted: 2012-08-29
• Last Update Posted: 2012-08-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• age between 18 and 60 years
• BMI between 23 and 28 kg/m2
• dietary unrestraint (TFEQ: F1<9)

Exclusion Criteria

• age under 18 and above 60 years
• BMI under 23 and above 28 kg/m2
• dietary restraint (TFEQ: F1>9)
• use of medication
• pregnant or breastfeeding

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
food intake	on testday 0 and 13

Secondary Outcome Measures

Name	Time	Method
appetite profile ratings	on test day 0, 8 and 13 (at 16 time points)
satiety hormones (GLP-1 and PYY)	on test day 0 and 13 (at 9 time points

Trial Locations

Locations (1)

Maastricht University; 🇳🇱 Maastricht, Limburg, Netherlands