Effect of High-calcium Intake on Appetite, Insulinemia and Incretins
- Conditions
- Nutritional and Metabolic Diseases
- Interventions
- Dietary Supplement: Calcium
- Registration Number
- NCT01682343
- Lead Sponsor
- Northumbria University
- Brief Summary
The purpose of this study is to investigate the appetite, insulin and incretin hormone responses to a high-calcium meal.
- Detailed Description
Participants will be provided with control and high-calcium meals. Insulin, appetite, glucagon-like peptide-1 and glucose-dependent insulinotropic peptide responses will be assessed, along with rates of substrate oxidation.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 10
- recreationally active
- male
- food intolerances/allergies
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description High-Calcium Calcium As control, but with a high-calcium content.
- Primary Outcome Measures
Name Time Method Subjective appetite ratings 3 hour Subjective ratings of appetite assessed by visual analogue scales.
- Secondary Outcome Measures
Name Time Method Serum insulin concentration 2 hour 2 hour area under the curve for serum insulin following breakfast consumption
Plasma glucose-dependent insulinotropic peptide concentration 2 hour 2 hour area under the curve for plasma glucose-dependent insulinotropic peptide following breakfast consumption
Plasma glucagon-like peptide-1 concentration 2 hour 2 hour area under the curve for plasma glucagon-like peptide-1 following breakfast consumption
Trial Locations
- Locations (1)
Northumbria University
🇬🇧Newcastle upon Tyne, Tyne on Wear, United Kingdom