MedPath

Longitudinal Pancreatic Cancer Study

Completed
Conditions
Pancreatic Cancer
Registration Number
NCT02250638
Lead Sponsor
Fujirebio Diagnostics, Inc.
Brief Summary

To obtain sufficient specimens and correlating clinical data from a well-controlled prospective clinical trial collecting longitudinal specimens from subjects diagnosed with any stage of pancreatic cancer.

Detailed Description

The study objectives are described below:

1. Obtain serum and plasma specimens longitudinally collected from approximately 140 subjects diagnosed with pancreatic cancer and are about to or are currently undergoing treatment and follow-up. Specimens will be used to evaluate CA 19-9 assays, currently under development, as an aid for monitoring recurrence or progressive disease.

2. To store any remaining specimens for use in future cancer research and to evaluate as yet undetermined biomarkers for the development of IVDs, including additional CA 19-9 assays, for monitoring the course of disease and therapy in subjects diagnosed with pancreatic cancer.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
140
Inclusion Criteria
  • Males and females, age≥ 18 years
  • Histologic/pathologic confirmation of exocrine pancreatic cancer
  • Any stage of disease: Newly diagnosed, stable, disease progression
  • Any treatment time point: Treatment naïve, currently receiving or completed therapy for pancreatic cancer including active monitoring.
  • Individuals with a history of malignant disease other than pancreatic cancer that was resected greater than 5 years ago and are currently in remission are eligible.
  • Life expectancy greater than 6 months
  • Able to understand and willing to provide informed consent
Exclusion Criteria
  • Males and females, age <18 years
  • No histologic/pathologic confirmation of exocrine pancreatic cancer
  • Life expectancy less than 6 months
  • Any concurrent malignancy other than basal or squamous cell skin cancers or in-situ cervical cancer.
  • Unable to provide informed consent

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
A Prospective Longitudinal Study of CA 19-9 as an Aid in Monitoring Disease in Patients with Pancreatic Cancer3 years
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (7)

Harry & Jeanette Weinberg Cancer Institute

🇺🇸

Baltimore, Maryland, United States

GI Research Institute

🇨🇦

Vancouver, British Columbia, Canada

The Ohio State University

🇺🇸

Columbus, Ohio, United States

Kansas City VA Center

🇺🇸

Kansas City, Missouri, United States

Boca Raton Regional Hospital

🇺🇸

Boca Raton, Florida, United States

Broward Health Medical Center

🇺🇸

Fort Lauderdale, Florida, United States

New Hanover Regional Medical Center

🇺🇸

Wilmington, North Carolina, United States

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