A Comparison of Weighted Vest Exercise and Strength Training

Phase 3

Completed

• Conditions: Mobility Limitations; Aging

• Registration Number: NCT00158119
• Lead Sponsor: National Institute on Aging (NIA)

Brief Summary

The purpose of this study is to evaluate two types of exercise therapy designed to improve muscle power and mobility: weighted vest exercise vs. progressive resistance training.

Detailed Description

Muscle power, a separate physical attribute from strength, is an important determinate of physical functioning in the elderly, for example in avoiding impending falls, rising from a chair, and climbing stairs. Muscle power, which declines with aging at a different rate than strength, has been shown in previous studies to improve through power training utilizing specially designed exercise equipment. However, weighted vest exercise could provide an acceptable, low cost, readily accessible alternative.

The hypotheses being tested in this study are: 1) weighted vest exercise will improve lower extremity power when compared to age matched controls in a standardized progressive resistance training program; 2) improvements in lower extremity power enhance functional performance as shown by improved gait velocity, stair climbing, and chair rise time; and 3) weighted vest exercise in impaired older adults will improve self-reported function and disability.

One hundred sixty-four men and women ages 65 and older, with some physical limitation but able to climb stairs independently, will be randomized to one of two 16-week exercise programs. The intervention group will participate in a weighted vest exercise protocol, consisting of chair-based and stair-climbing exercise, while the control group will participate in a standardized progressive resistance training program. Participants in both programs will meet three times per week for 30-60 minutes per session, for a total of 16 weeks, at a research exercise gym, and will be under the direct supervision of research staff.

Study Timeline

• Study Start: 2001-07
• Study First Submitted: 2005-09-07
• Study First Submitted QC: 2005-09-07
• Study First Posted: 2005-09-12
• Primary Completion: 2007-09
• Study Completion: 2007-09
• Status Verified: 2010-07
• Last Update Submitted: 2010-07-23
• Last Update Posted: 2010-07-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

• Community dwelling men and women aged 65 or older
• Ability to provide informed consent
• Impairment in physical performance, based on a score between 4 and 10 inclusive on the SPPB (Short Physical Performance Battery), which evaluates standing balance, walking speed, and chair-rise time
• Score of 24 or greater on the Folstein mini-mental status exam
• Exhibit independent stair-climbing ability

Exclusion Criteria

• Unstable acute or chronic disease
• Neuromusculoskeletal impairment interfering with independent stair climbing
• Abdominal aortic aneurysm
• Exertional angina
• History of ventricular arrhythmia
• Inguinal or abdominal hernia
• Symptomatic valvular heart disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
balance measured at baseline, 8 weeks, and 16 weeks
endurance
Leg power
leg strength
mobility

Secondary Outcome Measures

Name	Time	Method
Disability

Trial Locations

Locations (1)

Spaulding Cambridge Outpatient Center; 🇺🇸 Cambridge, Massachusetts, United States