JPRN-jRCTs031180437已完成2 期
Metachronous gastric cancer prevention with aspirin:A multi-center randomized trial - MEGA trial
Gotoda Takuji0 个研究点目标入组 50 人开始时间: 2019年3月27日最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 50
研究概览
简要总结
This study was discontinued.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 <= 80age old（—）
- 性别
- All
入选标准
- •1) Achieved absolute or expanded curative resection with ESD defined as per JGCA guidelines
- •2) Aged 20-80 years
- •3) Performance Status (ECOG) 0, 1, or 2
- •4) H. pylori infection was eradicated within 5 years or negative before enrollment
- •5) Will be followed over 5 years
- •6) Written informed consent
排除标准
- •1) Allergy to aspirin treatment
- •2) A history of H. pylori eradication therapy received more than 5 years ago
- •3) Lesions of Siewert Type II (<2 cm from the OGJ at the epicenter)
- •4) A history of gastric surgery
- •5) Severe co-morbidities and estimated life expectancy less than 3 years
- •6) Already on aspirin or other antithrombotic drugs prior to randomization
- •7) Using NSAIDs
- •8) Using Metformin
- •9) A history of peptic ulcers
- •10) A history of stroke
- •11) Receiving chemotherapy
- •12) Disorder of blood coagulation or platelet < 100,000/microliter
- •13) Pregnancy
- •14) Breast-feeding
- •15) Lack of informed consent
研究者
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