Effects of tDCS on Quadriceps Strength After Stroke

Not Applicable

Completed

• Conditions: Stroke
• Interventions: Device: transcranial Direct current stimulation

• Registration Number: NCT02109796
• Lead Sponsor: Centre d'Investigation Clinique et Technologique 805

Brief Summary

Previous studies show that one session of tDCS allow to improve muscle strength in hemiparetic patients in anodal condition. We test a new electrods configuration : a anodale stimulation opposite to the cortical representation area of the injured hemisphere and a simultaneous stimulation opposite to the homonyme the cortical representation area of the healthy hemisphere. This approach seems to be the best relevant electrods configuration in order to restore the inter-hemispheric balance.

We hypothesis that one session of tDCS with this electrods configuration allow to improve paretic quadriceps strength in hemiparetic patients after stroke.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2014-04-08
• Study First Submitted QC: 2014-04-09
• Study First Posted: 2014-04-10
• Study Start: 2015-02-19
• Primary Completion: 2016-11-28
• Study Completion: 2017-04-30
• Status Verified: 2017-11
• Last Update Submitted: 2017-11-10
• Last Update Posted: 2017-11-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• written consent
• hemiparetic patient after stroke in chronic phase (> 6 months)
• capacity to walk with or without technical assistance
• following rehabilitation program for lower limbs

Exclusion Criteria

• patient with bilateral brain lesion, cerebellar syndrom, and apraxia and/or aphasia
• previous orthopedic surgery in paretic lower limb (<6 moths)
• usual tDCS contraindications
• pregnant woman

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
hemiplegic patient	transcranial Direct current stimulation	anodal transcranial direct current stimulation
patient control	transcranial Direct current stimulation	Sham transcranial direct current stimulation

Primary Outcome Measures

Name	Time	Method
maximum voluntary isometric strength of knee extensors	2 hours	The maximum voluntary isometric strength of paretic knee extensors will be evaluated with a isokinetic dynamometer, which measure peak torque.

Secondary Outcome Measures

Name	Time	Method
Resistive peak torque during passive knee flexion	2h
Angle related to the resistive peak torque generation of the knee extensors	2h
Amplitude of the interpolation twitch	2h
EMG activation of the knee flexors and extensors during the strength evaluations (active and passive)	2h
Functional evaluation of the gait performance and balance	2h

Trial Locations

Locations (1)

Raymond Poincare Hospital; 🇫🇷 Garches, France